It's a competition Bosham have a fond association, winning on five occasions - most recently in 2017/18 - when a late Matt Andrews goal defeated Rustington 1-0 at Pagham.
A date for the tie against the Brighton-based club is yet to be confirmed, with the winners facing a trip to Jarvis Brook in the quarter finals.
The full draw can be viewed via the link below:
SCFL DIVISION TWO CHALLENGE CUP - DRAW IN FULL
Bosham get their SCFL Division Two season up-and-running away at St Francis Rangers, on August 17, before getting an earlier date in at Montpelier Villa on August 24 (both 3pm k.o's)
OPENING FIXTURES - IN-FULL (inc pre-season)